Moraci A, Buonaiuto C, Punzo A, Parlato C, Amalfi R
Institute of Neurosurgery, First Medical School, University of Naples, Italy.
Neurochirurgia (Stuttg). 1992 Mar;35(2):48-53. doi: 10.1055/s-2008-1052245.
The authors analyze the results they obtained by percutaneous radiofrequency technique for trigeminal neuralgia. The clinical material consists of 605 cases observed from 1977 to 1986 at their Institute. There was a female preponderance (62%) and an average age of 65 years. Idiopathic, atypical and symptomatic trigeminal neuralgia has been diagnosed respectively in 568, 21 and 16 cases. From 1977 to 1980 the working temperature was above 65 C, thereafter a lower temperature has been employed to coagulate the Gasserian ganglion. The rate of pain relief was 97% for idiopathic trigeminal neuralgia, 75% for symptomatic and 21% for atypical. The loss of facial sensation accounts for 80% of side effects of this procedure in their series. The recurrence of pain was observed in 16% of cases with a follow-up ranging from 2 to 10 years. It is noteworthy that there is a correlation between the coagulation temperature and the rate of recurrence, the higher the former, the lower the latter. The authors compare their results (rate of pain relief, morbidity, mortality, rate of recurrence) with those of major reports in the literature concerning either percutaneous or other surgical procedures (mircosurgical decompression of the trigeminal nerve, glycerol injection into the trigeminal cistern and percutaneous microcompression).
作者分析了经皮射频技术治疗三叉神经痛所获得的结果。临床资料包括1977年至1986年在他们研究所观察的605例病例。女性占优势（62%），平均年龄为65岁。特发性、非典型性和症状性三叉神经痛分别诊断出568例、21例和16例。1977年至1980年工作温度高于65℃，此后采用较低温度凝固半月神经节。特发性三叉神经痛的疼痛缓解率为97%，症状性的为75%，非典型性的为21%。在他们的系列研究中，面部感觉丧失占该手术副作用的80%。随访2至10年，16%的病例观察到疼痛复发。值得注意的是，凝固温度与复发率之间存在相关性，前者越高，后者越低。作者将他们的结果（疼痛缓解率、发病率、死亡率、复发率）与文献中关于经皮或其他外科手术（三叉神经显微外科减压、甘油注入三叉神经池和经皮微压迫）的主要报告结果进行了比较。
