Kukuk P, Lungenhausen M, Molsberger A, Endres H G
Department of Medical Informatics, Statistics and Epidemiology, Ruhr University Bochum, Germany.
Eur J Med Res. 2005 Jun 22;10(6):263-72.
Little is known about potential long-term effects of body acupuncture. The aim of the study was to determine such long-term effects 3 and 6 months after the end of a course of acupuncture treatment for chronic low-back pain (cLBP) or chronic pain caused by gonarthrosis.
Prospective cohort study with patients who had received 10 sessions of needle body acupuncture within a maximum of 10 weeks. Data source was our survey of all patients receiving acupuncture treatment in Germany. A total of 1096 eligible patients with cLBP or gonarthrosis pain were identified (68.1% female) and invited by letter to participate in the study. Ultimately 249 patients remained, with no loss of representativeness. Two telephone interviews were conducted 3 and 6 months after the last acupuncture session using standardized questionnaires, available as electronic case report forms. The primary target criteria were self-assessment of pain tolerability prior to the start of acupuncture and after the end of treatment, and pain intensity (GCPS) over time. Secondary target criteria were changes to functional impairment (HFAQ for cLBP, WOMAC for gonarthrosis), quality of life (SF12), depression (CES-D) and patient global assessment of treatment effectiveness (PGA). For the indication cLBP, pain-related fear avoidance beliefs (FABQ) were also queried.
Pain tolerability before acupuncture was reported as being significantly worse than pain tolerability at the time of the two post-acupuncture interviews. The scores for all post-acupuncture questionnaires showed no significant changes over time, with the exception of treatment effectiveness for gonarthrosis. Mean scores for each of the questionnaires at the 3 and 6 month follow-up interviews were as follows: cLBP: Pain tolerability (pre: 6.8, post: 3.4 / 3.4), pain intensity (41.8 / 42.6), PGA (2.4 / 2.6), SF12 physical (35.8 / 35.8), SF12 mental (45.3 / 46.9), CES-D (14.9 / 14.9), HFAQ (67.2 / 67.1), FABQ total (2.9 / 2.9). GONARTHROSIS: Pain tolerability (pre: 6.9, post: 3.6 / 3.9), pain intensity (42.9 / 42.8), PGA (2.6 / 2.9), SF12 physical (32.2 / 31.3), SF12 mental (45.0 / 46.2), CES-D (15.6 / 14.7), WOMAC total (34.6 / 34.0).
Pain tolerability was significantly improved after acupuncture and remained so up to 6 months after treatment. The mean scores of almost all questionnaires did not change significantly between 3 and 6 months. We therefore conclude that acupuncture had a long-term effect on important aspects of cognitive and emotional pain coping.
关于体针疗法潜在的长期影响,人们了解甚少。本研究的目的是确定在针对慢性下腰痛(cLBP)或膝关节病引起的慢性疼痛进行一个疗程的针灸治疗结束后3个月和6个月时的此类长期影响。
对在最多10周内接受了10次体针治疗的患者进行前瞻性队列研究。数据来源是我们对德国所有接受针灸治疗患者的调查。共确定了1096例符合条件的cLBP或膝关节病疼痛患者(68.1%为女性),并通过信函邀请他们参与研究。最终有249例患者参与,无代表性损失。在最后一次针灸治疗后3个月和6个月进行了两次电话访谈,使用标准化问卷,这些问卷可作为电子病例报告表获取。主要目标标准是针灸开始前和治疗结束后的疼痛耐受性自我评估,以及随时间变化的疼痛强度(全球慢性疼痛分级量表,GCPS)。次要目标标准是功能障碍的变化(cLBP用汉密尔顿功能障碍问卷,HFAQ;膝关节病用西安大略和麦克马斯特大学骨关节炎指数,WOMAC)、生活质量(SF-12)、抑郁(流调中心抑郁量表,CES-D)以及患者对治疗效果的总体评估(PGA)。对于cLBP这一适应症,还询问了与疼痛相关的恐惧回避信念(FABQ)。
据报告,针灸前的疼痛耐受性明显差于两次针灸后访谈时的疼痛耐受性。除膝关节病的治疗效果外,所有针灸后问卷的得分随时间均无显著变化。在3个月和6个月随访访谈时,各问卷的平均得分如下:cLBP:疼痛耐受性(治疗前:6.8,治疗后:3.4 / 3.4),疼痛强度(41.8 / 42.6),PGA(2.4 / 2.6),SF-12身体维度(35.8 / 35.8),SF-12心理维度(45.3 / 46.9),CES-D(14.9 / 14.9),HFAQ(67.2 / 6