睑缘炎患者与正常人群中蠕形螨的患病率。

The Prevalence of Demodex folliculorum in blepharitis patients and the normal population.

作者信息

Kemal Mustafa, Sümer Zeynep, Toker Mustafa Ilker, Erdoğan Haydar, Topalkara Aysen, Akbulut Makbule

机构信息

Department of Ophthalmology, Cumhuriyet University School of Medicine, Sivas, Turkey.

出版信息

Ophthalmic Epidemiol. 2005 Aug;12(4):287-90. doi: 10.1080/092865805910057.

DOI:10.1080/092865805910057

PMID:16033750

Abstract

PURPOSE

Demodex folliculorum (DF), which is frequently found in patients with chronic blepharitis, is a well-known common inhabitant of eyelash follicles. In the present study, the prevalence of DF in seborrheic blepharitis patients and controls was investigated. In addition, the associations between the presence of DF and host factors (age, sex) were analyzed.

METHODS

A prospective, cross-sectional study was done involving 500 cases. In all, 6000 cilia from 170 patients with seborrheic blepharitis and 330 patients with normal eyes were examined for DF. Twelve eyelash samples were epilated from each patient and examined under the light microscope.

RESULTS

DF was found in 28.8% (49/170) of patients with blepharitis and in 26.7% (88/330) of controls. The difference between the two groups was not statistically significant. The overall prevalence was 27.4% (137/500) in all patients. Although the prevalence of DF increased with increasing age, no significant difference was found between the age groups. There was also no statistically significant difference for DF prevalence between males (28.9%; 71/246) and females (24.1%; 61/254).

CONCLUSION

Our findings show a high DF prevalence in both blepharitis and control patients and no relationship was found between the presence of DF and host factors (age, sex).

摘要

目的

毛囊蠕形螨（DF）是睫毛毛囊中常见的寄居菌，在慢性睑缘炎患者中也经常被发现。在本研究中，调查了脂溢性睑缘炎患者和对照组中DF的患病率。此外，还分析了DF的存在与宿主因素（年龄、性别）之间的关联。

方法

进行了一项前瞻性横断面研究，涉及500例病例。总共对170例脂溢性睑缘炎患者和330例眼部正常患者的6000根睫毛进行了DF检查。从每位患者身上拔除12根睫毛样本，在光学显微镜下进行检查。

结果

睑缘炎患者中有28.8%（49/170）检测到DF，对照组中有26.7%（88/330）检测到DF。两组之间的差异无统计学意义。所有患者的总体患病率为27.4%（137/500）。虽然DF的患病率随年龄增长而增加，但各年龄组之间未发现显著差异。男性（28.9%；71/246）和女性（24.1%；61/254）的DF患病率也无统计学显著差异。