Foti Caterina, Calvario Agata, d'Ovidio Roberto, Bonamonte Domenico, Scarasciulli Maria Luisa, Conserva Anna, Casulli Claudia, Angelini Giovanni
Department of Internal Medicine, Immunology and Infectious Diseases, Unit of Dermatology, University of Bari, Italy.
New Microbiol. 2005 Apr;28(2):157-9.
We report the case of a 70-year-old man with a 1 year history of relapsing folliculitis of the scalp. Bacteriological, mycological and the Tzanck tests from the lesions were negative. Histopathological study showed suppurative perifollicular flogosis. Virological cultures were negative, while HSV nested polymerase chain reaction (nPCR) assays made on swabs and histological sections from the scalp lesions demonstrated the presence of herpes simplex virus type-2 (HSV-2) in all samples. Skin swabs of healthy areas yielded negative results for HSV-2 infection. The folliculitis showed a marked and quick improvement after therapy with famciclovir suggesting a possible etiologic role of HSV-2 in the scalp folliculitis.
我们报告了一例70岁男性，有1年复发性头皮毛囊炎病史。病变部位的细菌学、真菌学及Tzanck试验均为阴性。组织病理学研究显示化脓性毛囊周围炎。病毒培养阴性，而对头皮病变部位的拭子和组织切片进行的单纯疱疹病毒2型（HSV-2）巢式聚合酶链反应（nPCR）检测显示，所有样本中均存在HSV-2。健康部位的皮肤拭子HSV-2感染检测结果为阴性。使用泛昔洛韦治疗后，毛囊炎有明显且迅速的改善，提示HSV-2在头皮毛囊炎中可能起病因学作用。
