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成功的辅助生殖治疗对向父母角色转变过程中男性和女性心理健康的影响:一项前瞻性对照研究。

The impact of successful assisted reproduction treatment on female and male mental health during transition to parenthood: a prospective controlled study.

作者信息

Repokari L, Punamäki R-L, Poikkeus P, Vilska S, Unkila-Kallio L, Sinkkonen J, Almqvist F, Tiitinen A, Tulppala M

机构信息

Hospital for Children and Adolescents, Helsinki University Central Hospital, Finland.

出版信息

Hum Reprod. 2005 Nov;20(11):3238-47. doi: 10.1093/humrep/dei214. Epub 2005 Jul 21.

Abstract

BACKGROUND

The dynamics of mental health during the transition to parenthood have not been a focus of research. Our prospective longitudinal study was designed to reveal whether there are differences in mental health during the transition to parenthood between parents undergoing treatment with assisted reproduction techniques (ART) and those who conceive spontaneously.

STUDY GROUP

367 couples with a singleton ART pregnancy using their own gametes.

CONTROL GROUP

379 couples with a spontaneous singleton pregnancy. Men and women separately filled in questionnaires including the General Health Questionnaire: at the 18th-20th week of pregnancy, 2 months postpartum and 1 year postpartum (T3). The effect of social and child-related factors on mental health was examined.

RESULTS

ART women had fewer depressive symptoms during pregnancy than controls, but at T3 their depressive symptoms were at the same level as seen in controls. Anxiety symptoms increased among control but not among ART women across the transition. ART men reported generally fewer mental health symptoms than their controls. Social and child-related stressors had negative impacts on mental health changes among control couples, whereas no impact was found among ART couples.

CONCLUSIONS

Successful ART did not predict mental health problems during the transition to parenthood. Moreover, ART couples' mental health was remarkably resistant to social and child-related stress during the transition to parenthood.

摘要

背景

为人父母过渡阶段的心理健康动态变化尚未成为研究重点。我们的前瞻性纵向研究旨在揭示接受辅助生殖技术(ART)治疗的父母与自然受孕的父母在为人父母过渡阶段的心理健康是否存在差异。

研究组

367对使用自身配子通过ART单胎妊娠的夫妇。

对照组

379对自然单胎妊娠的夫妇。男性和女性分别填写问卷,包括一般健康问卷:在妊娠第18 - 20周、产后2个月和产后1年(T3)。研究了社会和与孩子相关的因素对心理健康的影响。

结果

ART女性在孕期的抑郁症状少于对照组,但在T3时,她们的抑郁症状与对照组处于同一水平。在整个过渡阶段,对照组女性的焦虑症状增加,而ART女性没有。ART男性报告的心理健康症状总体上少于对照组。社会和与孩子相关的压力源对对照组夫妇的心理健康变化有负面影响,而在ART夫妇中未发现影响。

结论

成功的ART并不能预测为人父母过渡阶段的心理健康问题。此外,在为人父母过渡阶段,ART夫妇的心理健康对社会和与孩子相关的压力具有显著的抵抗力。

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