Mazza Marianna, Kotzalidis Georgios D, Avallone Carla, Balocchi Marta, Sessa Ilenia, De Luca Ilaria, Hirsch Daniele, Simonetti Alessio, Janiri Delfina, Loi Emanuela, Marano Giuseppe, Albano Gabriella, Fasulo Vittorio, Borghi Stefania, Del Castillo Angela Gonsalez, Serio Anna Maria, Monti Laura, Chieffo Daniela, Angeletti Gloria, Janiri Luigi, Sani Gabriele
Institute of Psychiatry and Psychology, Department of Geriatrics, Neuroscience and Orthopedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Department of Psychiatry, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
J Pers Med. 2022 Sep 28;12(10):1598. doi: 10.3390/jpm12101598.
Since the identification of Couvade syndrome in the late 1950s, little attention has been dedicated to the issue of depression in expecting fathers.
To quantify the extent of depression in expecting fathers and find out if they match their pregnant partners' depression.
We conducted a PubMed and ClinicalTrials.gov search using paternal depression and all its variants as terms. We used the referred eporting tems for ystematic Reviews and eta-nalyses () 2020 statement to include eligible studies.
We identified a grand total of 1443 articles, of which 204 were eligible. The total number of fathers/expecting fathers involved was 849,913. Longitudinal studies represented more than half of the included studies; more than three-quarters of the studies used the Edinburgh Postnatal Depression Scale (EPDS). The average occurrence of paternal depression was around 5%, which confers the entity some clinical dignity. Depression tends to occur more in expecting women and new mothers than in expecting partners or new fathers, while the co-occurrence in the same couple is quite low.
The methodological heterogeneity of the included studies prevents us from meta-analyzing the obtained data. The validity of the instruments used is another issue.
Paternal depression is distinct from maternal depression and occurs at lower rates (about half). The very existence of a paternal depression clinical entity is beyond any doubt. Future research should address methodological heterogeneity.
自20世纪50年代末识别出拟娩综合征以来，准父亲的抑郁问题很少受到关注。
量化准父亲的抑郁程度，并了解他们是否与其怀孕伴侣的抑郁程度相符。
我们在PubMed和ClinicalTrials.gov上进行检索，使用“父亲抑郁”及其所有变体作为检索词。我们使用系统评价和Meta分析的首选报告项目（PRISMA）2020声明来纳入符合条件的研究。
我们共识别出1443篇文章，其中204篇符合条件。涉及的父亲/准父亲总数为849913人。纵向研究占纳入研究的一半以上；超过四分之三的研究使用爱丁堡产后抑郁量表（EPDS）。父亲抑郁的平均发生率约为5%，这赋予了该疾病一定的临床重要性。抑郁在孕妇和新妈妈中比在准父亲或新爸爸中更易发生，而同一对伴侣中同时出现抑郁的情况相当少见。
纳入研究的方法学异质性使我们无法对所得数据进行Meta分析。所用工具的有效性是另一个问题。
父亲抑郁与母亲抑郁不同，发生率较低（约为一半）。父亲抑郁这一临床实体的存在不容置疑。未来的研究应解决方法学异质性问题。
