Sorrentino Giacoma C, Caffari Bruno, Vanacore Nicola, Maggini Marina, Raschetti Roberto
Centro Nazionale di Epidemiologia, Sorveglianza e Promozione della Salute, Istituto Superiore di Sanita, Via Giano della Bella 34, 00161 Rome, Italy.
Ann Ist Super Sanita. 2005;41(1):63-8.
The Cronos Project is a post-marketing surveillance study implemented by the Italian Ministry of Health and the National Institute of Health whose main objectives are to characterise the population of Alzheimer's disease patients treated with acetylcholinesterase inhibitors and monitor effectiveness and drug safety in the field practice. In this project 503 Alzheimer's disease units were activated located throughout the country. The characteristics of these Alzheimer's disease units are presented for setting (territorial, university, hospital, extra-hospital), health personnel employed, examinations offered (CT and MRI scans and laboratory tests), counselling activities and relationship with caregiver associations in relation to neuropsychological tests.
克罗诺斯项目是一项由意大利卫生部和国家卫生研究院开展的上市后监测研究，其主要目标是对接受乙酰胆碱酯酶抑制剂治疗的阿尔茨海默病患者群体进行特征描述，并在实际应用中监测疗效和药物安全性。在该项目中，全国范围内启动了503个阿尔茨海默病治疗单元。本文介绍了这些阿尔茨海默病治疗单元的特征，包括设置情况（地区性、大学附属、医院、院外）、所雇佣的卫生人员、提供的检查项目（CT和MRI扫描以及实验室检查）、咨询活动以及在神经心理测试方面与护理者协会的关系。
