[半乳糖凝集素-3在侵袭性催乳素瘤中的表达]
[Expression of galectin-3 in invasive prolactinomas].
作者信息
Wang Hong, Wang Ming-dong, Ma Wen-bin, Yang Di, Shi Yan-Fang, Kong Yan-guo, Li Shi-fang, Li Zhi-hong, Wang Ren-zhi
机构信息
Department of Neurosurgery, Affiliated Hospital of Hebei Medical College for Continuous Education, Baoding 071000, China.
出版信息
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Jun;27(3):380-1.
OBJECTIVE
To investigate the expression of galectin-3 (Gal-3) in prolactinomas.
METHODS
Expressions of Gal-3 were evaluated by immunohistochemistry using polyclonal antibody in 16 invasive prolactinomas and 16 prolactinomas.
RESULTS
Gal-3 was expressed both in invasive prolactinomas and noninvasive prolactinomas while significantly higher expression seen in the invasive prolactinomas (P < 0.05).
CONCLUSION
Gal-3 expression may be used as a useful indicator to determine the invasiveness and prognosis of prolactinomas.
目的
研究半乳糖凝集素-3（Gal-3）在催乳素瘤中的表达。
方法
采用多克隆抗体免疫组织化学法评估16例侵袭性催乳素瘤和16例催乳素瘤中Gal-3的表达。
结果
Gal-3在侵袭性催乳素瘤和非侵袭性催乳素瘤中均有表达，而侵袭性催乳素瘤中的表达明显更高（P < 0.05）。
结论
Gal-3表达可作为判断催乳素瘤侵袭性和预后的有用指标。
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