No evidence of plasticity in hair follicles of recipients after allogeneic hematopoietic stem cell transplantation.

作者信息

Rovó Alicia, Meyer-Monard Sandrine, Heim Dominik, Arber Caroline, Passweg Jakob R, Gratwohl Alois, Tichelli André

机构信息

Division of Hematology, University Hospital Basel, Basel, Switzerland.

出版信息

Exp Hematol. 2005 Aug;33(8):909-11. doi: 10.1016/j.exphem.2005.04.010.

Here we show in a prospective quantitative study of 115 patients after allogeneic hematopoietic stem cell transplantation that hair follicles remain exclusively of recipient type despite full whole blood donor-type chimerism. Our data indicate that unmanipulated hematopoietic donor stem cells do not contribute directly to reconstitution even in an organ at highest need for repair.