Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Tennoudai, Tsukuba 305-8575, Ibaraki, Japan.
J Cataract Refract Surg. 2005 Jun;31(6):1133-8. doi: 10.1016/j.jcrs.2004.10.059.
To evaluate the clinical usefulness of 11-deoxycortisol, a precursor of cortisol in steroid metabolism, in visualizing the vitreous body in the anterior chamber after posterior capsule rupture during cataract surgery.
Department of Ophthalmology, Tsukuba University Hospital, Ibaraki, Japan.
Eight eyes had anterior vitrectomy during cataract surgery using this new technique. A suspension of 11-deoxycortisol was prepared by dilution in balanced salt solution without preservatives or emulsifying agents. After a posterior capsule rupture, the suspension was injected into the anterior chamber. The visual and anatomical outcomes of surgery were evaluated during a follow-up of 7 to 9 months.
After the 11-deoxycortisol injection, the vitreous body that had prolapsed through the torn posterior capsule, with white particles entrapped on its surface, became clearly visible. Complete removal of the prolapsed vitreous body was achieved easily and safely using an anterior vitrectomy system. No postoperative complications related to the use of 11-deoxycortisol were observed.
Injection of 11-deoxycortisol helped visualize the vitreous body in the anterior chamber after posterior capsule rupture. The technique minimized intraoperative and postoperative complications related to posterior capsule rupture and vitreous loss during cataract surgery [corrected]
评估 11-脱氧皮质醇（皮质醇代谢中的前体）在白内障手术中后囊破裂导致玻璃体进入前房时用于玻璃体可视化的临床应用价值。
日本茨城县筑波大学医院眼科。
使用这项新技术，8 只眼在白内障手术中进行了前玻璃体切除术。通过在不含防腐剂或乳化剂的平衡盐溶液中稀释来制备 11-脱氧皮质醇混悬液。后囊破裂后，将混悬液注入前房。在 7 至 9 个月的随访期间，评估手术的视觉和解剖结果。
11-脱氧皮质醇注射后，通过撕裂的后囊脱出的玻璃体，其表面带有白色颗粒，变得清晰可见。使用前玻璃体切除术系统可以轻松、安全地完全清除脱出的玻璃体。未观察到与使用 11-脱氧皮质醇相关的术后并发症。
注射 11-脱氧皮质醇有助于在白内障手术中后囊破裂后可视化前房内的玻璃体。该技术最大限度地减少了与白内障手术中后囊破裂和玻璃体丢失相关的术中及术后并发症[纠正]。
