Serretti Alessandro, Olgiati Paolo, Colombo Cristina
Department of Psychiatry, Istituto Scientifico H San Raffaele, Vita-Salute University, Via Stamira D'Ancona 20, 20127 Milano, Italy.
J Affect Disord. 2005 Sep;88(1):93-8. doi: 10.1016/j.jad.2005.05.008.
Decrease in self-esteem (SE) is found in all mood disorders during inter-episode phases. This trait was associated with relapse and suicidality but its genetic basis is still undefined, probably because SE has multiple components. The aim of the current study was to ascertain which of those components were altered in a sample of affective patients. Three hundred and thirty-one outpatients with bipolar (N=199) and major depressive MD (N=132) disorders in remission for at least three months and one hundred controls completed the Rosenberg Self-esteem Scale (RSE; [Rosenberg, M., 1965. The measurement of self-esteem, Society and the Adolescent Self-Image. Princeton University Press, pp.16-36]). Principal component analysis was performed to identify RSE factor structure. Extracted factors were compared across case and control groups in the whole sample (N=431) and in a sub-sample (N=301) with low self-esteem (RSE <20). PCA yielded a two-factor solution with self-confidence (SC) and self-deprecation (SD) that was largely consistent with the existing literature. Such factors were both associated with lower scores in affective patients than controls (SC: F=52, p<0.01; SD: F=43, p<0.01). However in the low RSE group only self-confidence was found to be decreased in subjects with mood disorders (SC: F=13.8, p<0.01; SD: F=0.05, p=0.9). These findings suggest that self-esteem deficit in affective disorders might involve specific components. Implications for research and clinical practice are discussed.
在所有心境障碍的发作间期阶段均发现自尊(SE)下降。这一特征与复发及自杀行为相关,但其遗传基础仍不明确,可能是因为自尊具有多个组成部分。本研究的目的是确定在情感障碍患者样本中,哪些组成部分发生了改变。331名双相情感障碍(N = 199)和重度抑郁障碍(MD,N = 132)且病情缓解至少三个月的门诊患者以及100名对照者完成了罗森伯格自尊量表(RSE;[罗森伯格,M.,1965年。自尊的测量,《社会与青少年自我形象》。普林斯顿大学出版社,第16 - 36页])。进行主成分分析以确定RSE的因子结构。在整个样本(N = 431)以及自尊较低(RSE < 20)的子样本(N = 301)中,对病例组和对照组的提取因子进行比较。主成分分析得出了一个包含自信(SC)和自我贬低(SD)的双因子解决方案,这在很大程度上与现有文献一致。与对照组相比,情感障碍患者在这些因子上的得分均较低(SC:F = 52,p < 0.01;SD:F = 43,p < 0.01)。然而,在低RSE组中,仅发现心境障碍患者的自信降低(SC:F = 13.8,p < 0.01;SD:F = 0.05,p = 0.9)。这些发现表明,情感障碍中的自尊缺陷可能涉及特定组成部分。讨论了对研究和临床实践的启示。