Ratcliff Graham, Colantonio Angela, Escobar Michael, Chase Susan, Vernich Lee
HealthSouth Harmarville Rehabilitation Hospital, Pittsburgh, PA, USA.
Disabil Rehabil. 2005 Mar 18;27(6):305-14. doi: 10.1080/09638280400018338.
The study used a retrospective cohort design to establish long-term mortality rates and predictors of mortality for persons after moderate to severe traumatic brain injury (TBI).
Consecutive records of persons with moderate to severe TBI who were discharged from a large rehabilitation hospital in Pittsburgh, Pennsylvania in the years 1974-1984, 1988 and 1989 were reviewed.
Six hundred and forty-two eligible individuals were identified and mortality was ascertained up to 24 years post injury. One hundred and twenty-eight of these individuals were found to be deceased. Poisson regression analyses revealed at least a 2-fold increased risk for mortality compared to the general population. Pre-injury characteristics and levels of disability at discharge from in-patient rehabilitation were among the strongest predictors of mortality.
These data constitute evidence for premature death in the post-acute TBI population following a moderate to severe head injury and are discussed in relation to other research in the area.
本研究采用回顾性队列设计，以确定中度至重度创伤性脑损伤（TBI）患者的长期死亡率及死亡预测因素。
回顾了1974 - 1984年、1988年和1989年从宾夕法尼亚州匹兹堡一家大型康复医院出院的中度至重度TBI患者的连续记录。
确定了642名符合条件的个体，并确定了受伤后长达24年的死亡率。其中128人已死亡。泊松回归分析显示，与一般人群相比，死亡风险至少增加了两倍。受伤前特征和住院康复出院时的残疾水平是最强的死亡预测因素。
这些数据证明了中度至重度头部受伤后急性TBI患者过早死亡，并与该领域的其他研究进行了讨论。
