Phillips A N, Smith G D
Department of Public Health and Primary Care, Royal Free Hospital School of Medicine, London, U.K.
Stat Med. 1992 May;11(7):953-61. doi: 10.1002/sim.4780110712.
A series of graphs is presented that show the estimated degree of bias in logistic coefficient estimates for two correlated continuous exposures measured with imprecision. These graphs indicate that even when the correlation coefficient between the exposure of interest and a correlated exposure is as low as 0.2, imprecision in the measurement of the latter exposure can result in at least as serious bias in the logistic coefficient estimate for the exposure of interest as measurement imprecision in the exposure of interest itself. The implications for the design and interpretation of epidemiological studies are discussed.
呈现了一系列图表,这些图表展示了针对两个以不精确方式测量的相关连续暴露,逻辑系数估计值中的偏差估计程度。这些图表表明,即使感兴趣的暴露与相关暴露之间的相关系数低至0.2,后一种暴露测量中的不精确性在感兴趣暴露的逻辑系数估计中所导致的偏差,可能至少与感兴趣暴露自身测量中的不精确性所导致的偏差一样严重。文中还讨论了对流行病学研究设计和解读的影响。