Rink C
Klinik und Poliklinik für Innere Medizin, Martin-Luther-Universität, Halle.
Schweiz Rundsch Med Prax. 1992 Jun 9;81(24):798-9.
The basic therapeutic principle in alcoholic liver diseases in general and in alcoholic hepatitis in particular is the consequent withdrawal of alcohol intake. Basic therapy of more complicated causes includes well balanced nutrition and symptomatic treatment according to the known principles of hepatology and intensive care medicine. Infusions with glucose-glucagon-insulin, or the administration of silymarin, and in individual cases of glucocorticoids seems to be justified as additional treatment. The therapy with S-adenosyl-L-methionine is promising, but clear evidence of the therapeutic effect has to be supplied by clinical studies. Liver transplantation should be taken into consideration in prognostically infaust cases.
一般而言,酒精性肝病尤其是酒精性肝炎的基本治疗原则是持续戒酒。对于更为复杂病因的基础治疗包括均衡营养以及根据肝病学和重症医学的已知原则进行对症治疗。静脉输注葡萄糖-胰高血糖素-胰岛素、服用水飞蓟素,在个别情况下使用糖皮质激素作为辅助治疗似乎是合理的。S-腺苷-L-蛋氨酸疗法前景良好,但临床研究必须提供其治疗效果的确切证据。对于预后不良的病例应考虑肝移植。