Charmes J P, Ton That H, Rince M, Dupré-Goudable C, Durand D
Service de néphrologie-hémodialyse, CHU Dupuytren, Limoges.
Rev Prat. 1992 Feb 15;42(4):427-31.
Risk factors for heart disease in patients with chronic renal failure (CRF) are the same as in general population; moreover CRF and renal replacement therapies (dialysis, immunosuppressive drugs for kidney transplantation) induce further specific cardiac risks. In practice, the commonest heart diseases associated with CRF are coronary artery diseases, myocardiopathies from various aetiologies, valve diseases and arrhythmias. Uremic pericarditis are quite unusual nowadays. Advances in therapy authorize easier control of congestive heart failure, the major complication of heart disease in CRF patients. Furthermore, it was observed that correction of anemia with erythropoietin therapy or kidney transplantation can ameliorate or reverse partially some cardiac diseases.
慢性肾衰竭(CRF)患者患心脏病的风险因素与普通人群相同;此外,CRF和肾脏替代疗法(透析、肾移植的免疫抑制药物)会引发更多特定的心脏风险。实际上,与CRF相关的最常见心脏病是冠状动脉疾病、各种病因引起的心肌病、瓣膜疾病和心律失常。如今,尿毒症心包炎相当罕见。治疗方面的进展使充血性心力衰竭(CRF患者心脏病的主要并发症)更容易得到控制。此外,观察发现,用促红细胞生成素疗法纠正贫血或进行肾移植可部分改善或逆转某些心脏病。