骨肉瘤
[Osteosarcoma].
作者信息
Kalifa C
机构信息
Service de pédiatrie, Institut Gustave-Roussy, Villejuif.
出版信息
Rev Prat. 1992 Apr 1;42(7):823-6.
PMID:1604201
Abstract
Osteosarcoma is the most frequent malignant tumor of bones. The peak incidence is in the second decade and the metaphyseal part of long bones is the site of predilection. This tumor is spontaneously rapidly fatal but recent progresses in chemotherapy and surgery have improved its prognosis (for example initial chemotherapy with high dose methotrexate and postoperative chemotherapy adapted to the histological response of the resected tumor to preoperative treatment).
摘要
骨肉瘤是最常见的骨恶性肿瘤。发病高峰在第二个十年，长骨干骺端是好发部位。这种肿瘤如不治疗会迅速致命，但近年来化疗和手术方面的进展改善了其预后（例如采用高剂量甲氨蝶呤进行初始化疗，并根据切除肿瘤对术前治疗的组织学反应进行术后化疗）。
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