体外培养的血吸虫卵肉芽肿分泌巨噬细胞融合因子（MFF）。
Secretion of macrophage fusion factor (MFF) by schistosome egg granulomas maintained in vitro.
作者信息
Rodriguez-Acosta A, Girón M E, Aguilar I
机构信息
Universidad Central de Venezuela, Instituto de Medicina Tropical, Caracas.
出版信息
Scand J Immunol. 1992 Jun;35(6):633-6. doi: 10.1111/j.1365-3083.1992.tb02968.x.
Abstract
The schistosome granuloma cultured in vitro under antigenic specific and unspecific stimulation releases macrophage fusion factor (MFF) into the medium, adjusting the production dynamics to the spontaneous modulation model already described. These findings demonstrate the feasibility of studying granulomatous response in mammalian schistosomiasis utilizing an in vitro model of lymphokine granuloma secretion.
摘要
在抗原特异性和非特异性刺激下体外培养的血吸虫肉芽肿会将巨噬细胞融合因子（MFF）释放到培养基中，使其产生动态变化符合已描述的自发调节模型。这些发现证明了利用淋巴细胞因子肉芽肿分泌的体外模型研究哺乳动物血吸虫病肉芽肿反应的可行性。
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