Ovbiagele Bruce, Saver Jeffrey L
Department of Neurology, UCLA Medical Center, Los Angeles, CA, USA.
Neurology. 2005 Jul 26;65(2):293-5. doi: 10.1212/01.wnl.0000168163.72351.f3.
Smokers with acute myocardial infarction have better outcomes after thrombolysis than nonsmokers. The authors evaluated the independent effect of smoking on short-term outcome following IV thrombolysis for acute ischemic stroke. After adjusting for covariates, recent smokers who received thrombolysis had a significantly greater drop in 24-hour median stroke severity scores from baseline than nonsmokers who received thrombolysis and lower mortality over 1 year.
急性心肌梗死患者溶栓后的预后比非吸烟者更好。作者评估了吸烟对急性缺血性卒中静脉溶栓后短期预后的独立影响。在对协变量进行调整后,接受溶栓治疗的近期吸烟者在24小时内的卒中严重程度中位数评分较基线的下降幅度显著大于接受溶栓治疗的非吸烟者,且1年内的死亡率更低。