Peeters Justine K, Van der Spek Peter J
Department of Bioinformatics, Erasmus MC, University Medical Centre Rotterdam Dr Molewaterplein 50, 3015GE Rotterdam, The Netherlands.
Cell Biochem Biophys. 2005;43(1):149-66. doi: 10.1385/CBB:43:1:149.
In today's field of genomics, traditional gene-by-gene approach is not adequate to meet the demand of processing information generated from mapping the complex biology of the human genome. More global views of analyzing the magnitude of information are necessary, such as with microarrays. Microarray technology today is rapidly uncovering broad patterns of genetic activity and showing insight into gene functions, processes, and pathways. With the growing technology, imminent knowledge is being generated looking into transcriptional processes and biological mechanisms from many different organisms and phylogeny. Many tools are being developed to assist with the analysis of such high-throughput data, many applications are being utilized by this technology, and the field is growing and expanding rapidly to accommodate the expanding genomics era.
在当今的基因组学领域，传统的逐个基因研究方法已不足以满足处理人类基因组复杂生物学图谱所产生信息的需求。需要更全面地分析信息规模，比如使用微阵列技术。如今，微阵列技术正在迅速揭示广泛的基因活动模式，并深入了解基因功能、过程和通路。随着该技术的不断发展，正在产生关于许多不同生物体和系统发育的转录过程及生物学机制的新知识。人们正在开发许多工具来辅助分析此类高通量数据，该技术正在被应用于诸多领域，并且该领域正在迅速发展和扩展，以适应不断扩展的基因组学时代。
