Oiso N, Fukai K, Ishii M, Hayashi T, Uda H, Imanishi M
Department of Dermatology, Saiseikai Tondabayashi Hospital, Japan.
Clin Exp Dermatol. 2005 Sep;30(5):523-4. doi: 10.1111/j.1365-2230.2005.01862.x.
We report a case of acquired smooth muscle hamartoma (ASMH) of tunica dartos, believed to be only the fifth so far reported. A 24-year-old man had a 6-month history of an asymptomatic tight and thickened scrotum. The skin was difficult to pinch. A biopsy specimen from the skin showed increased and proliferated smooth-muscle bundles composed of well-differentiated and uniform spindle cells that showed typical features of acquired smooth muscle hamartoma. Interestingly, dilatations of the lymph vessels were noted in the upper dermis above the proliferated smooth muscles. It has been reported recently that long-standing severe lymphoedema may cause histological features mimicking ASMH. As the present case was not preceded by oedema of the scrotum, we consider this case to be true ASMH.
我们报告一例肉膜性获得性平滑肌瘤（ASMH），据信这是迄今为止报道的第五例。一名24岁男性有6个月无症状阴囊紧绷增厚的病史。阴囊皮肤难以捏起。皮肤活检标本显示平滑肌束增多且增生，由分化良好且形态一致的梭形细胞组成，呈现出获得性平滑肌瘤的典型特征。有趣的是，在增生的平滑肌上方的真皮上层可见淋巴管扩张。最近有报道称，长期严重的淋巴水肿可能导致类似ASMH的组织学特征。由于本例之前并无阴囊水肿，我们认为该病例为真正的ASMH。
