Sánchez-Morillas L, Reaño Martos M, Rodríguez Mosquera M, Iglesias Cadarso A, Domínguez Lázaro A R
Servicio de Alergología, Clínica Puerta de Hierro, San Martín de Porres, Madrid, Spain.
Allergol Immunopathol (Madr). 2005 Jul-Aug;33(4):224-7. doi: 10.1157/13077748.
To determine the incidence and nature of adverse events associated with the induction of rush Hymenoptera venom immunotherapy.
Between 1998 and 2003, we administered venom immunotherapy to 48 patients allergic to bee or wasp venom, by means of a rush immunotherapy protocol (3 days).
We observed no severe adverse reactions in any patients. 12 patients developed only local reactions at the site of injections that did not required any pharmacological treatment. Two patients experienced mild systemic reactions consisting of diffuse urticaria on day 3. Both adverse reactions were treated with intravenous antihistamines.
Our experience confirms that rapid venom immunotherapy is safe and should be considered in every case especially for patients during the stinging insect season when a rapid protection is required.
确定与快速蜂毒免疫疗法诱导相关的不良事件的发生率和性质。
1998年至2003年期间，我们通过快速免疫疗法方案（3天）对48例对蜜蜂或黄蜂毒液过敏的患者进行了毒液免疫治疗。
我们在任何患者中均未观察到严重不良反应。12例患者仅在注射部位出现局部反应，无需任何药物治疗。2例患者在第3天出现轻度全身反应，表现为弥漫性荨麻疹。两种不良反应均用静脉注射抗组胺药治疗。
我们的经验证实，快速毒液免疫疗法是安全的，在每种情况下都应予以考虑，尤其是在蛰虫季节需要快速保护的患者。
