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异时性肝细胞癌和早期食管癌病例报告

Case report of metachronous hepatocellular carcinoma and early esophageal cancer.

作者信息

Takahashi Ken, Yoshida Hiroshi, Mamada Yasuhiro, Taniai Nobuhiko, Nakamura Yoshiharu, Mizuguchi Yoshiaki, Miyashita Masao, Nomura Tsutomu, Makino Hiroshi, Tajiri Takashi

机构信息

Surgery of Organ Function and Biological Regulation, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.

出版信息

J Nippon Med Sch. 2005 Jun;72(3):187-90. doi: 10.1272/jnms.72.187.

Abstract

We report a case of double cancer of the liver and esophagus, an extremely rare condition that can be very difficult to treat. A tumorous lesion was pointed out in segment 6 of the liver of a 69-year-old man under treatment for liver cirrhosis. Abdominal computed tomography and angiography revealed a hepatocellular carcinoma. The patient underwent transcatheter arterial embolization and partial resection of segments 5 and 6. Fourteen months later, a small elevated lesion was detected in the esophagus during an endoscopic examination. The patient was treated by endoscopic mucosal resection and radiation therapy at a total dose of 50 Gy. Histological examination revealed a squamous cell carcinoma with cancer cells confined within the epithelium of the esophagus. Over the 6 years since the hepatectomy, there have been no signs of recurrence. We report a successful curative resection in an extremely rare form of double cancer with a poor prognosis.

摘要

我们报告一例肝和食管双原发癌病例,这是一种极为罕见且治疗难度极大的疾病。一名69岁正在接受肝硬化治疗的男性患者,其肝脏第6段发现一个肿瘤性病变。腹部计算机断层扫描和血管造影显示为肝细胞癌。该患者接受了经导管动脉栓塞术以及第5和第6段的部分切除术。14个月后,在内镜检查中发现食管有一个小的隆起性病变。患者接受了内镜黏膜切除术和总剂量为50 Gy的放射治疗。组织学检查显示为鳞状细胞癌,癌细胞局限于食管上皮内。肝切除术后6年,未见复发迹象。我们报告了一例预后不良的极为罕见的双原发癌成功根治性切除病例。

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