Dujmović Irena, Svetel Marina, Petrović Igor, Stefanova Elka, Koprivsek Katarina, Kozić Dusko, Kostić Vladimir
Klinicki centar Srbije, Institut za neurologiju, Beograd, Srbija i Crna Gora.
Vojnosanit Pregl. 2005 Jun;62(6):487-90. doi: 10.2298/vsp0506487d.
Acute exposure to the effects of volatile solvents is characterized by the abrupt onset of symptoms and signs of poisoning, and relatively fast recovery in the majority of cases.
We report a 24-year-old patient with an acute, accidental poisoning with a mixture of volatile organic solvents (most probably toluene, styrene and xylene), which led to the development of upward gaze paresis, diplopia, hemiparesis, ataxic gate, and the late onset truncal ataxia episodes. After 6 weeks, he recovered completely, while his extensive brain MRI lesions in the caudate nuclei, laterobasal putaminal regions, bilateral anterior insular cortex, central midbrain tegmental area) withdrew completely after 4 months.
Acute toxic encephalopathy should be a part of the differential diagnosis in any patient with acute neurobehavioral and neurological deficit.
急性接触挥发性溶剂的影响表现为中毒症状和体征突然出现，且大多数情况下恢复相对较快。
我们报告一名24岁患者，因意外急性中毒，接触了挥发性有机溶剂混合物（很可能是甲苯、苯乙烯和二甲苯），导致出现上视麻痹、复视、偏瘫、共济失调步态以及迟发性躯干共济失调发作。6周后，他完全康复，而其在尾状核、外侧基底节区、双侧前岛叶皮质、中脑中央被盖区广泛的脑MRI病变在4个月后完全消退。
急性中毒性脑病应作为任何有急性神经行为和神经功能缺损患者鉴别诊断的一部分。
