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小儿脑肿瘤的内镜治疗

Endoscopic management of pediatric brain tumors.

作者信息

Souweidane Mark M

机构信息

Department of Neurological Surgery, Weill Medical College of Cornell University, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

出版信息

Neurosurg Focus. 2005 Jun 15;18(6A):E1. doi: 10.3171/foc.2005.18.6.2.

DOI:10.3171/foc.2005.18.6.2
PMID:16048285
Abstract

OBJECT

Primary endoscopic procedures for children with intraventricular brain tumors include endoscopic tumor biopsy and endoscopic tumor removal. The simultaneous treatment of hydrocephalus with endoscopic third ventriculostomy (ETV) or endoscopic septostomy increases the appeal of a minimally invasive endoscopic approach.

METHODS

Eighty-five patients who underwent endoscopic management of an intraventricular brain tumor were identified from a prospective database. Of these patients, 26 were younger than 21 years of age at the time of diagnosis. The surgical technique, its success rate, and patient outcome were assessed. Illustrative cases are used in this study to detail the procedure of endoscopic tumor biopsy and resection. Endoscopic tumor procedures were successful in 96% of cases (23 of 24 endoscopic tumor biopsy samples and both endoscopic tumor removals). Fourteen simultaneous procedures were performed to treat hydrocephalus successfully. There was no recognized morbidity from the surgical procedures.

CONCLUSIONS

Endoscopic surgery in children with intraventricular brain tumors is an effective and safe method for sampling of the lesion and, in select cases, its resection. This minimally invasive technique should be considered in situations in which the patient might thereby avoid a more conventional procedure, given the high rate of success and low morbidity associated with endoscopic management.

摘要

目的

儿童脑室内肿瘤的主要内镜手术包括内镜肿瘤活检和内镜肿瘤切除。通过内镜下第三脑室造瘘术(ETV)或内镜下隔膜造瘘术同时治疗脑积水,增加了微创内镜手术的吸引力。

方法

从一个前瞻性数据库中确定了85例行脑室内肿瘤内镜治疗的患者。其中,26例在诊断时年龄小于21岁。评估了手术技术、成功率和患者预后。本研究使用了一些典型病例来详细说明内镜肿瘤活检和切除的过程。内镜肿瘤手术在96%的病例中成功(24例内镜肿瘤活检样本中的23例以及2例内镜肿瘤切除术均成功)。成功进行了14例同时治疗脑积水的手术。手术未出现公认的并发症。

结论

儿童脑室内肿瘤的内镜手术是一种有效且安全的病变取样方法,在某些情况下还可进行病变切除。鉴于内镜治疗成功率高且并发症少,对于可能避免更传统手术的患者,应考虑采用这种微创技术。

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