Jabri Bana, Kasarda Donald D, Green Peter H R
Department of Pathology, Medicine and Pediatrics, University of Chicago, Chicago, IL 60637, USA.
Immunol Rev. 2005 Aug;206:219-31. doi: 10.1111/j.0105-2896.2005.00294.x.
Celiac disease is a multigenetic complex inflammatory disorder with an autoimmune component, induced by gluten, a protein found in wheat. It is a unique human disease model to dissect the innate and adaptive immune mechanisms underlying T-cell-mediated tissue destruction and the development of T-cell lymphoma in conditions of chronic T-cell activation.
乳糜泻是一种具有自身免疫成分的多基因复杂炎症性疾病，由小麦中的一种蛋白质——麸质诱发。它是一种独特的人类疾病模型，用于剖析在慢性T细胞激活情况下T细胞介导的组织破坏以及T细胞淋巴瘤发生背后的固有免疫和适应性免疫机制。
