Venturini Alessandro, Zane Cristina, Rodella Rosita, Leali Carla, Calzavara Pinton Piergiacomo, Zorzi Fausto
Department of Dermatology, Spedali Civili, p.le Spedali Civili, 1 25123 Brescia, Italy.
Eur J Dermatol. 2005 Jul-Aug;15(4):262-4.
Syringotropic cutaneous T cell Lymphoma (SCTCL) is a rare localized variant of CTCL. It is characterized by erythematous papules that, at histological examination, show dense dermal infiltrates of atypical T cells, that are preferentially located around hyperplastic eccrine sweat glands and ducts, with absent or minimal epidermotropism. Its relationship with mycosis fungoides and other CTCLs is not clarified and is still under discussion. Several treatment approaches have been suggested, but therapeutic results are often disappointing. We report the case of a patient with typical clinical and histopathological features of SCTCL and an excellent response to PUVA therapy.
向汗腺性皮肤T细胞淋巴瘤（SCTCL）是蕈样肉芽肿（CTCL）的一种罕见局限性变体。其特征为红斑丘疹，组织学检查显示真皮有密集的非典型T细胞浸润，这些细胞优先位于增生的小汗腺和导管周围，表皮趋向性缺失或极少。其与蕈样霉菌病及其他CTCL的关系尚不明确，仍在讨论中。已提出多种治疗方法，但治疗结果往往令人失望。我们报告了1例具有典型SCTCL临床和组织病理学特征且对补骨脂素加紫外线A（PUVA）疗法反应良好的患者。
