Mitteldorf C, Bertsch H P, Kretschmer L
Hautklinik und Poliklinik der Georg-August-Universität Göttingen, Göttingen.
Hautarzt. 2006 Jul;57(7):625-7. doi: 10.1007/s00105-005-0998-2.
Leiomyosarcomas are derived from smooth muscles and only rarely involve the skin. A 73-year-old male presented with progressive tumor painful on the chest which had been present for 3 years and was tender to palpation, a finding more often associated with benign leiomyomas. immunohistochemical staining demonstrated multiple nerve fibers entrapped by atypical myofibrils, perhaps explaining the tenderness. Since 1996, we have excised five painless cutaneous leiomyosarcomas, in which entrapped nerves could not be demonstrated.
平滑肌肉瘤起源于平滑肌,很少累及皮肤。一名73岁男性,胸部出现进行性肿瘤,已存在3年,触诊时有压痛,这一表现更常见于良性平滑肌瘤。免疫组化染色显示非典型肌原纤维包绕多条神经纤维,这可能是压痛的原因。自1996年以来,我们已切除5例无痛性皮肤平滑肌肉瘤,其中未发现有神经纤维包绕。