糖尿病视网膜病变治疗对毛细血管床再灌注的影响

[Effects of treatment for diabetic retinopathy on reperfusion of the capillary bed].

作者信息

Sugiyama Wakako, Ando Noburo

机构信息

Department of Ophthalmology, Saiseikai Niigata Daini Hospital, Japan.

出版信息

Nippon Ganka Gakkai Zasshi. 2005 Jul;109(7):428-33.

PMID:16050461

Abstract

PURPOSE

We studied the effects of treatment for diabetic retinopathy on reperfusion and obstruction of the capillary bed.

SUBJECT AND METHODS

In a retrospective study, we studied fluorescein angiograms of 66 patients (98 eyes) with diabetic retinopathy treated in our hospital between January 1998 and July 2002. Fluorescein angiography was performed at the first visit and each treatment (vitrectomy, photocoagulation, and follow-up). Angiographic findings of reperfusion and obstruction in the temporal raphe area were evaluated.

RESULTS

In the patients who had undergone vitrectomy, reperfusion of the capillary bed was observed in 10 of 24 (42%) eyes and regularity or obstruction was observed in 14 (58%). In the patients treated by photocoagulation, reperfusion was observed in 11 of 56 (20%) eyes and regularity or obstruction was observed in 45 (80%). In the patients without treatment, reperfusion was observed in 1 of 18 (6 %) eyes and regularity or obstruction was observed in 17 (94%).

CONCLUSION

Reperfusion of the capillary bed was significantly greater in the vitrectomy patients than in the photocoagulation and follow-up patients. Treatment for diabetic retinopathy influenced reperfusion and obstruction of the capillary bed in the temporal raphe area.

摘要

目的

我们研究了糖尿病视网膜病变的治疗对毛细血管床再灌注和阻塞的影响。

对象与方法

在一项回顾性研究中，我们研究了1998年1月至2002年7月间在我院接受治疗的66例（98只眼）糖尿病视网膜病变患者的荧光素血管造影图像。在首次就诊时以及每次治疗（玻璃体切除术、光凝治疗和随访）时进行荧光素血管造影。评估颞侧中缝区域再灌注和阻塞的血管造影结果。

结果

接受玻璃体切除术的患者中，24只眼中有10只（42%）观察到毛细血管床再灌注，14只（58%）观察到规则性或阻塞。接受光凝治疗的患者中，56只眼中有11只（20%）观察到再灌注，45只（80%）观察到规则性或阻塞。未接受治疗的患者中，18只眼中有1只（6%）观察到再灌注，17只（94%）观察到规则性或阻塞。