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骨骼肌细胞分化过程中的乳酸转运:L6肌管中特定载体的证据。

Lactate transport during differentiation of skeletal muscle cells: evidence for a specific carrier in L6 myotubes.

作者信息

el Abida K, Duvallet A, Thieulart L, Rieu M, Beaudry M

机构信息

Laboratoire de physiologie des adaptations, CHU Cochin, Paris, France.

出版信息

Acta Physiol Scand. 1992 Apr;144(4):469-71. doi: 10.1111/j.1748-1716.1992.tb09322.x.

DOI:10.1111/j.1748-1716.1992.tb09322.x
PMID:1605048
Abstract

Cellular uptake of lactate involves a carrier in numerous types of mammalian cells. In cultured rat L6 myoblasts, lactate diffuses freely. We show that during myogenesis a carrier appears at the myotube stage. The degree of cellular differentiation was determined by microscopic observation and by measurement of a marker of biochemical differentiation: the increase in specific activity of creatine kinases.

摘要

乳酸的细胞摄取在多种哺乳动物细胞中涉及一种载体。在培养的大鼠L6成肌细胞中,乳酸可自由扩散。我们发现,在肌生成过程中,一种载体在肌管阶段出现。通过显微镜观察以及测量生化分化标志物:肌酸激酶比活性的增加来确定细胞分化程度。

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Lactate transport during differentiation of skeletal muscle cells: evidence for a specific carrier in L6 myotubes.骨骼肌细胞分化过程中的乳酸转运:L6肌管中特定载体的证据。
Acta Physiol Scand. 1992 Apr;144(4):469-71. doi: 10.1111/j.1748-1716.1992.tb09322.x.
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Lactate transport in skeletal muscle cells: uptake in L6 myoblasts.骨骼肌细胞中的乳酸转运:L6成肌细胞中的摄取
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