Steyaert J, Borghgraef M, Gaulthier C, Fryns J P, Van den Berghe H
Division of Child Psychiatry, University of Leuven, Belgium.
Am J Med Genet. 1992;43(1-2):116-9. doi: 10.1002/ajmg.1320430117.
Here we present the results of the study of the cognitive profile of 11 adult, normally intelligent female fragile X [fra(X)] carriers. In all individuals 3 types of testing were performed: full scale Wechsler Adult Intelligence Scale, a set of neuropsychological tests and an arithmetic achievement test. All 11 subjects showed an average to above-average intelligence but 10 of 11 performed better on the performance than on the verbal subscale. Neuropsychological tests suggest a dysfunction of the reticulo-thalamic axis with deficiency on tests requiring visual memory and a pronounced deficiency of attention skills combined with an impulsive way of completing tests.
在此，我们展示了对11名成年、智力正常的女性脆性X染色体[fra(X)]携带者认知特征的研究结果。对所有个体进行了3种测试：韦氏成人智力量表全量表、一套神经心理学测试和一项算术成绩测试。所有11名受试者的智力均处于平均水平或高于平均水平，但11人中有10人在操作量表上的表现优于言语量表。神经心理学测试表明，网状丘脑轴功能障碍，在需要视觉记忆的测试中存在缺陷，注意力技能明显不足，且在完成测试时有冲动行为。
