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A profile of cognitive deficit in females from fragile X families.

作者信息

Miezejeski C M, Jenkins E C, Hill A L, Wisniewski K, French J H, Brown W T

出版信息

Neuropsychologia. 1986;24(3):405-9. doi: 10.1016/0028-3932(86)90026-6.

DOI:10.1016/0028-3932(86)90026-6
PMID:3736823
Abstract

Fragile X, a recently discovered X-linked syndrome, is usually associated with mental retardation in affected males. Less consistent findings have been described for females. neuropsychological evaluation of seven nonretarded females from fragile X families suggested a characteristic profile: on Wechsler IQ tests, a positive Verbal-Performance score difference and lower subtest scaled scores on Arithmetic, Digit Span, Block Design, and Object Assembly; on the Wide Range Achievement Test, a lower score on Arithmetic than on Reading or Spelling; and on the Benton Visual Retention Test, defective recall. These results suggest the existence of X-linked learning disability in females.

摘要

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