Pitts Marian, Grierson Jeffrey, Misson Sebastian
Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Victoria, Australia.
AIDS Patient Care STDS. 2005 Jul;19(7):460-5. doi: 10.1089/apc.2005.19.460.
The advent of highly active antiretroviral therapy means that we now have people living with HIV/AIDS (PLWHA) living longer, many of them surviving into old age. There has been relatively little attention paid to people aging with HIV. This study reports on a group of Australian PLWHA aged 50 years and over. They are compared to younger PLWHA on a range of social dimensions. Older PLWHA were significantly less likely to rate their health and well-being as good or excellent. A significantly larger percentage of older PLWHA reported additional health conditions (47.2% versus 35.5%), of which the most common was cardiovascular disease (12.2% of older PLWHA). There was no significant difference in the percentage of older PLWHA who reported a mental health condition. Younger PLWHA were significantly more likely to have been diagnosed with hepatitis C (15.3% versus 8.1% for older PLWHA). Older PLWHA were markedly less likely to be in contact with services, both those that were HIV related and those that were not. The financial circumstances of older PLWHA were significantly worse than for younger PLWHA, and personal support through a regular sexual relationship was also significantly less. The clinical and community needs of this group of PLWHA are likely to be of increasing concern. The challenges associated with this group will be the consequence both of the effects of long-term therapy, with potentially toxic side effects, and the natural aging process.
高效抗逆转录病毒疗法的出现意味着我们现在有更多感染艾滋病毒/艾滋病的人(PLWHA)寿命延长,其中许多人活到老年。人们对感染艾滋病毒的老年人关注相对较少。本研究报告了一组年龄在50岁及以上的澳大利亚PLWHA。在一系列社会层面上,将他们与年轻的PLWHA进行了比较。年龄较大的PLWHA将自己的健康和幸福评为良好或优秀的可能性明显较低。报告有其他健康状况的年龄较大的PLWHA比例显著更高(47.2%对35.5%),其中最常见的是心血管疾病(年龄较大的PLWHA中有12.2%)。报告有心理健康状况的年龄较大的PLWHA比例没有显著差异。年轻的PLWHA被诊断出感染丙型肝炎的可能性明显更高(15.3%对年龄较大的PLWHA中的8.1%)。年龄较大的PLWHA与服务机构(包括与艾滋病毒相关的和无关的)接触的可能性明显更低。年龄较大的PLWHA的经济状况明显比年轻的PLWHA更差,通过定期性关系获得的个人支持也明显更少。这组PLWHA的临床和社区需求可能会越来越受到关注。与这组人相关的挑战将是长期治疗的影响(可能有有毒副作用)和自然衰老过程共同作用的结果。