He Jian-Hui, Cai Le, Cui Wen-Long, Song Ying, Zhao Ke-Ying, Yang Jing-Jing, Zhou Hong-Mei, Li Tian-Shu
Department of Health Management, School of Public Health, Kunming Medical University, Kunming 650500, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2012 Mar;46(3):241-5.
To explore the quality of life among people living with HIV/AIDS (PLWHA) and analyze the influencing factors in Kunming.
A cross-sectional survey was conducted from March to April in year 2011, and 247 PLWHA were selected by convenience sampling from Yunnan CDC, Yunnan and Kunming infectious disease hospitals. General questionnaires, the simplified Chinese edition of medical outcomes study-HIV health survey (MOS-HIV, including 11 dimensions) and Social Support Scale were used. t test and multivariable linear regression model were used to analyze the results.
For the subjects investigated, the age was (39.8 +/- 11.9) years old, the median (quartile) value of symptoms related to HIV infection was 1(2). As to the scores of quality of life measured by MOS-HIV, physical summary score was 47.4 +/- 11.2, mental summary score was 43.6 +/- 9.7; for the scores of 11 dimensions of the MOS-HIV,that were general health (42.9 +/- 19.9), physical function (79.4 +/- 24.9), role function (59.8 +/- 48.2), social function (67.0 +/- 33.6), cognitive function (71.0 +/- 25.4), pain (81.3 +/- 26.2), mental health (62.0 +/- 22.3), vitality (49.3 +/- 23.8), health distress (74.4 +/- 21.0), quality of life (51.8 +/- 21.1), health transition (49.0 +/- 29.8). The total score of social support was 28.6 +/- 7.6, of which the score of subjective social support was 17.2 +/- 6.3, the score of the objective social support was 5.9 +/- 2.2; the score of the utilization of social support was 5.5 +/- 1.9. Multivariable linear regression analysis showed that the more the symptoms related to HIV infection, the lower the physical summary scores (standardized coefficients b' = -0.22), the general health (b' = - 0.31), the physical function (b' = -0.16), the role function (b' = -0.23), the pain (b' = -0.21), the mental health (b' = -0.22), the vitality (b' = -0.22) and the health distress scores (b' = - 0.24) (all P values < 0.05); the older the age, the lower the physical summary scores (b' = - 0.16), the mental summary scores (b' = - 0.16), the physical function (b' = -0.26), the vitality (b' = -0.26) and the quality of life scores (b' = -0.17) (all P values < 0.05); the higher the score of the subjective social support,the higher the physical summary scores (b' = 0.26), the mental summary scores (b' = 0.22), the general health (b' = 0.27), the social function (b' = 0.26), the mental health (b' = 0.15) and the quality of life scores (b' = 0.22) (all P values < 0.05); the higher the score of the utilization of social support, the higher the physical function (b' = 0.16) and the health transition scores (b' = 0.31) (all P values < 0.05).
PLWHA in Kunming have relatively lower scores of quality of life. A large number of symptoms during infection, older age and lower score of subjective social support were the hazard factors of quality of life in PLWHA.
探讨昆明市艾滋病病毒/艾滋病感染者(PLWHA)的生活质量,并分析其影响因素。
于2011年3月至4月进行横断面调查,采用方便抽样法从云南省疾病预防控制中心、云南省及昆明市传染病医院选取247例PLWHA。使用一般问卷、医学结局研究-艾滋病健康调查简版中文版(MOS-HIV,包括11个维度)和社会支持量表。采用t检验和多变量线性回归模型分析结果。
在被调查对象中,年龄为(39.8±11.9)岁,与HIV感染相关症状的中位数(四分位数)为1(2)。以MOS-HIV测量的生活质量得分中,生理综合评分为47.4±11.2,心理综合评分为43.6±9.7;MOS-HIV的11个维度得分分别为总体健康(42.9±19.9)、生理功能(79.4±24.9)、角色功能(59.8±48.2)、社会功能(67.0±33.6)、认知功能(71.0±25.4)、疼痛(81.3±26.2)、心理健康(62.0±22.3)、活力(49.3±23.8)、健康困扰(74.4±21.0)、生活质量(51.8±21.1)、健康转变(49.0±29.8)。社会支持总分28.6±7.6,其中主观社会支持得分为17.2±6.3,客观社会支持得分为5.9±2.2;社会支持利用度得分为5.5±1.9。多变量线性回归分析显示,与HIV感染相关的症状越多,生理综合评分越低(标准化系数b'=-0.22)、总体健康评分越低(b'=-0.31)、生理功能评分越低(b'=-0.16)、角色功能评分越低(b'=-0.23)、疼痛评分越低(b'=-0.21)、心理健康评分越低(b'=-0.22)、活力评分越低(b'=-0.22)以及健康困扰评分越低(b'=-0.24)(所有P值<0.05);年龄越大,生理综合评分越低(b'=-0.16)、心理综合评分越低(b'=-0.16)、生理功能评分越低(b'=-0.26)、活力评分越低(b'=-0.26)以及生活质量评分越低(b'=-0.17)(所有P值<0.05);主观社会支持得分越高,生理综合评分越高(b'=0.26)、心理综合评分越高(b'=0.22)、总体健康评分越高(b'=0.27)、社会功能评分越高(b'=0.26)、心理健康评分越高(b'=0.15)以及生活质量评分越高(b'=0.22)(所有P值<0.05);社会支持利用度得分越高,生理功能评分越高(b'=0.16)以及健康转变评分越高(b'=0.31)(所有P值<0.05)。
昆明市PLWHA的生活质量得分相对较低。感染期间出现大量症状、年龄较大以及主观社会支持得分较低是PLWHA生活质量的危险因素。