颌骨原发性骨内纤维肉瘤

Primary intraosseous fibrosarcoma of jaw.

作者信息

Pereira C M, Jorge J, Di Hipólito O, Kowalski L P, Lopes M A

机构信息

Oral Semiology and Oral Pathology, Department of Oral Diagnosis, School of Dentistry of Piracicaba/UNICAMP, Piracicaba, São Paulo, Brazil.

出版信息

Int J Oral Maxillofac Surg. 2005 Jul;34(5):579-81. doi: 10.1016/j.ijom.2004.10.015. Epub 2005 Jan 28.

DOI:10.1016/j.ijom.2004.10.015

PMID:16053882

Abstract

This paper reports one case of primary fibrosarcoma affecting the mandible in a 41-year-old woman. Microscopically, the tumor was cellularized with an intense mitotic activity, and areas of necrosis and hemorrhage, and the cells showed immunoreactivity only for vimentin, establishing the diagnosis of primary intraosseous fibrosarcoma. The patient underwent tumor surgical resection, supraomohyoid neck dissection and mandible reconstruction with fibula flap and titanium bar. She also received post-surgical radiotherapy and is in follow up for 36 months without signs of recurrence or metastases.

摘要

本文报道了一例41岁女性原发性纤维肉瘤累及下颌骨的病例。显微镜下，肿瘤细胞丰富，有强烈的有丝分裂活性，并有坏死和出血区域，细胞仅对波形蛋白呈免疫反应，从而确诊为原发性骨内纤维肉瘤。患者接受了肿瘤手术切除、肩胛舌骨肌上颈清扫术，并用腓骨瓣和钛棒进行了下颌骨重建。她还接受了术后放疗，目前已随访36个月，无复发或转移迹象。