Kaku Shoji, Takeshima Nobuhiro, Akiyama Futoshi, Furuta Reiko, Hirai Yasuo, Takizawa Ken
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.
Anticancer Res. 2007 Nov-Dec;27(6C):4365-9.
A unique fibrous tumor of the ovary is reported. A 32-year-old nulliparous woman was diagnosed with a left ovarian tumor and underwent left salpingo-oophorectomy. Macroscopically, the cut surface of the tumor showed yellowish multilobular areas. There was no sign of necrosis or hemorrhage within the tumor. Microscopically, the tumor consisted of two well-circumscribed components. One corresponded to the yellowish lobular areas; there were more than 10 mitotic figures per 10 high-power fields and strong staining for Ki-67, suggesting fibrosarcoma, but nuclear atypia was not severe. In the other component, there were few if any mitotic figures; there was no nuclear atypia and marked cellularity. Pathologically, the tumor was considered a variant fibrosarcoma or a mitotically active cellular fibroma. In light of these pathological findings along with the patient's age and obstetrical history, no further treatment was performed. There has been no evidence of recurrence after 1-year follow-up.
报告了一例独特的卵巢纤维瘤。一名32岁未生育女性被诊断为左侧卵巢肿瘤，并接受了左侧输卵管卵巢切除术。大体上，肿瘤切面显示为淡黄色多小叶区域。肿瘤内无坏死或出血迹象。显微镜下，肿瘤由两个界限清楚的成分组成。一个对应于淡黄色小叶区域；每10个高倍视野中有超过10个有丝分裂象，Ki-67染色强，提示纤维肉瘤，但核异型性不严重。在另一个成分中，几乎没有有丝分裂象；无核异型性且细胞丰富。病理上，该肿瘤被认为是纤维肉瘤变异型或有丝分裂活跃的细胞性纤维瘤。鉴于这些病理结果以及患者的年龄和产科病史，未进行进一步治疗。随访1年无复发证据。
