Holding the line on hepatic fat.
作者信息
Saltiel Alan R
出版信息
Cell Metab. 2005 Jul;2(1):1-2. doi: 10.1016/j.cmet.2005.06.010.
PMID:16054091
Abstract
When chronically elevated, insulin increases hepatic lipogenesis and VLDL synthesis. However, the hormone reduces liver lipids when acutely elevated. Work in this issue of Cell Metabolism (Najjar at al., 2005) suggests a new mechanism for the inhibition of the rate-limiting enzyme in liver, fatty acid synthase.
摘要
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