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儿童口腔扁平苔藓

Oral lichen planus in childhood.

作者信息

Laeijendecker Ronald, Van Joost Theodoor, Tank Bhupendra, Oranje Arnold P, Neumann H A Martino

机构信息

Department of Dermatology, Albert Schweitzer Hospital, Albert, Schweitzerplaats, The Netherlands.

出版信息

Pediatr Dermatol. 2005 Jul-Aug;22(4):299-304. doi: 10.1111/j.1525-1470.2005.22403.x.

Abstract

Oral lichen planus is rare in childhood, and only a few reports on this subject have appeared in the literature. Our objective was to report individual cases of oral lichen planus in childhood from our practice and to review the literature on this subject. We recruited patients younger than 18 years with oral lichen planus and documented several clinical aspects, the histopathology, patch tests, and blood examination findings. Three patients from about 10,000 dermatology patients younger than 18 years seen from 1994 to 2003 were included. Of these three, an Asian girl aged 11 years had an asymptomatic, hyperkeratotic variant of oral lichen planus, which disappeared without any treatment after 1 year. An Asian boy aged 16 years had an erosive oral lichen planus with severe pain, which healed after intensive local and systemic treatment in 2 years. A Caucasian girl aged 14 years had a hyperkeratotic variant with a little soreness, which disappeared with local treatment after 3 months. Our findings indicated that oral lichen planus in childhood is rare and therefore at present it is not possible to draw firm conclusions considering its nature and etiology. Oral lichen planus in childhood seems to occur preferentially in those of Asian race. The clinical features resemble those of oral lichen planus in adults. However, generally the prognosis of oral lichen planus in childhood seems to be more favorable than in adults.

摘要

口腔扁平苔藓在儿童中较为罕见,文献中仅有少数关于该主题的报道。我们的目的是报告我们诊所中儿童口腔扁平苔藓的个别病例,并回顾该主题的文献。我们招募了18岁以下患有口腔扁平苔藓的患者,并记录了几个临床方面、组织病理学、斑贴试验和血液检查结果。纳入了1994年至2003年间从约10000名18岁以下皮肤科患者中筛选出的3名患者。在这三名患者中,一名11岁的亚洲女孩患有无症状的口腔扁平苔藓角化过度型,1年后未经任何治疗自行消失。一名16岁的亚洲男孩患有糜烂性口腔扁平苔藓,伴有严重疼痛,经过2年的强化局部和全身治疗后痊愈。一名14岁的白种女孩患有角化过度型,稍有疼痛,经局部治疗3个月后消失。我们的研究结果表明,儿童口腔扁平苔藓较为罕见,因此目前无法就其性质和病因得出确凿结论。儿童口腔扁平苔藓似乎在亚洲种族人群中更易发生。其临床特征与成人口腔扁平苔藓相似。然而,总体而言,儿童口腔扁平苔藓的预后似乎比成人更有利。

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