Nazaruk Jolanta, Jakoniuk Piotr
Department of Pharmacognosy, Medical University of Białystok, Mickiewicza 2a Street, Białystok 15-089, Poland.
J Ethnopharmacol. 2005 Nov 14;102(2):208-12. doi: 10.1016/j.jep.2005.06.012. Epub 2005 Aug 2.
A new flavonoid compound isokaempferide 7-O-beta-d-(6''-methylglucuronide) (1) was isolated from flowers of Cirsium rivulare (Jacq.) All. Its structure was elucidated on the basis of spectroscopic studies (UV, (1)H and (13)C NMR, FABMS). Moreover, five known flavonoid compounds: apigenin 7-(6''-methylglucuronide) (2), hispidulin 7-glucoside (3), isokaempferide 7-glucuronide (4), kaempferol 3-galactoside (5), pectolinarin (6) were isolated from this source for the first time. The antimicrobial activity of aqueous, methanolic and 70% ethanolic extracts of Cirsium rivulare flowers and leaves was also evaluated.
从溪蓟（Cirsium rivulare (Jacq.) All.）的花中分离出一种新的黄酮类化合物异山柰酚7 - O - β - d -（6'' - 甲基葡萄糖醛酸苷）（1）。通过光谱研究（紫外光谱、¹H和¹³C核磁共振光谱、快原子轰击质谱）阐明了其结构。此外，还首次从该植物中分离出五种已知的黄酮类化合物：芹菜素7 -（6'' - 甲基葡萄糖醛酸苷）（2）、毛地黄黄酮7 - 葡萄糖苷（3）、异山柰酚7 - 葡萄糖醛酸苷（4）、山柰酚3 - 半乳糖苷（5）、果胶菌素（6）。还评估了溪蓟花和叶的水提取物、甲醇提取物和70%乙醇提取物的抗菌活性。
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