甲状腺功能亢进会加速特纳综合征患者的生长。

Hyperthyroidism accelerates growth in Turner's syndrome.

作者信息

Massa G, de Zegher F, Dooms L, Vanderschueren-Lodeweyckx M

机构信息

Department of Paediatrics, University of Leuven, Belgium.

出版信息

Acta Paediatr. 1992 Apr;81(4):362-4. doi: 10.1111/j.1651-2227.1992.tb12245.x.

DOI:10.1111/j.1651-2227.1992.tb12245.x

PMID:1606402

Abstract

Graves' disease in a girl with Turner's syndrome (karyotype 46,Xdel(Xp)) is described. Hyperthyroidism led to a pronounced acceleration of height velocity. During treatment with methimazole and L-thyroxine, height velocity normalized. The patient also developed spontaneous puberty with a clear-cut pubertal growth spurt. Final height, however, did not appear to be influenced either by Graves' disease or by spontaneous puberty.

摘要

本文描述了一名患有特纳综合征（核型46，Xdel(Xp)）的女孩患格雷夫斯病的情况。甲状腺功能亢进导致身高增长速度显著加快。在使用甲巯咪唑和L-甲状腺素治疗期间，身高增长速度恢复正常。该患者还出现了自发性青春期，并伴有明显的青春期生长突增。然而，最终身高似乎并未受到格雷夫斯病或自发性青春期的影响。