Meulders Q, Michel C, Marteau P, Grange J D, Mougenot B, Ronco P, Mignon F
Département de Néphrologie, Hôpital Tenon, Paris, France.
Clin Nephrol. 1992 May;37(5):239-44.
We report the case of a female patient with seronegative lupus and predominant bladder and intestinal involvement in the form of interstitial cystitis and protein-losing enteropathy. This association is exceptional in the literature but may be underestimated because of frequent latency of interstitial cystitis. It may define a peculiar subgroup of lupus patients usually responsive to steroid therapy. In this case, only cyclophosphamide markedly improved the protein-losing enteropathy but did not influence the bladder disease.
我们报告了一例血清阴性狼疮女性患者，其主要表现为间质性膀胱炎和蛋白丢失性肠病形式的膀胱和肠道受累。这种关联在文献中极为罕见，但可能因间质性膀胱炎的常见潜伏期而被低估。它可能定义了一组通常对类固醇治疗有反应的特殊狼疮患者亚组。在该病例中，仅环磷酰胺显著改善了蛋白丢失性肠病，但对膀胱疾病无影响。
