Nature. 1979 May 31;279(5712):431-3. doi: 10.1038/279431a0.
INCIDENTAL to investigations of chemical oncogenesis, we have observed that 3-methylcholanthrene (3-MC)-induced subcutaneous sarcogenesis occurred more rapidly in the axillary than in the inguinal region of the mouse. Recently Auerbach et al. have described what may be a similar phenomenon-a marked tendency for tumour transplants to grow better cephalically(1,2).
在化学致癌的研究过程中,我们发现,3-甲基胆蒽(3-MC)诱发的皮下肉瘤在小鼠的腋窝比腹股沟处生长得更快。最近 Auerbach 等人描述了一个可能类似的现象——肿瘤移植有明显向头侧生长更好的趋势(1,2)。