Berg D
Fortschr Med. 1992 Jan 30;110(3):67-8, 71-2.
The dilation of the femoral vein during pregnancy was analysed retrospectively in patients with unilateral severe varicose veins (group I, n = 7), mild varicose veins (group II, n = 8) and healthy pregnant women (group III, n = 3). Groups I and II employed elastic stockings as treatment, while group I additionally applied a ruscus-containing cream to the affected leg. In the healthy women, in the unaffected leg in group II and in the cream treated leg in group I, the femoral vein increased in diameter on average by 2.1 to 2.4 mm in the third term of pregnancy, while in the affected leg of group II it increased by 3.6; in group I the increase in the leg not treated with cream was about 4.5 mm. The differences in dilatation are significant (p less than 0.05). Apparently, the venous tonic action of ruscus extract can considerably reduce venous dilatation during pregnancy.
对患有单侧严重静脉曲张的患者（第一组，n = 7）、轻度静脉曲张患者（第二组，n = 8）和健康孕妇（第三组，n = 3）在孕期股静脉扩张情况进行回顾性分析。第一组和第二组采用弹力袜治疗，而第一组还对患侧腿部涂抹含贯叶金丝桃的乳膏。在健康女性、第二组未患病的腿部以及第一组涂抹乳膏治疗的腿部，股静脉直径在妊娠晚期平均增加2.1至2.4毫米，而第二组患侧腿部增加3.6毫米；第一组未涂抹乳膏的腿部增加约4.5毫米。扩张差异具有显著性（p < 0.05）。显然，贯叶金丝桃提取物的静脉张力作用可显著减轻孕期静脉扩张。
