Hargreaves J A
University of Alberta, Edmonton, Canada.
J Dent Res. 1992 May;71(5):1244-8. doi: 10.1177/00220345920710051801.
Material related to water fluoridation and fluoride availability has been examined for changing patterns of fluoride intake by humans over recent years. The difficulty of separating systemic and topical fluoride action from water and foods from that found in fluoride agents used in preventive treatment programs is discussed. Recommendations are made that water fluoridation is a well-proven program and should be continued, but that fluoride supplementation programs under the control of the individual should be carefully evaluated and, if used, should be restricted to periods after the secretory stage of enamel formation is normally finished for anterior teeth, with supplements commenced during the pre-eruption maturation period and continuing until permanent tooth eruption is complete. Although supplements can also give a topical source to the teeth, depending on the way the supplement is consumed and the duration of time it is available in the mouth, other methods of topical fluoride provision are endorsed, and these should continue through life. It is suggested, in respect of epidemiology studies, that data collected before the availability of fluoride dentifrices in 1971 should be re-examined.
近年来，已对与水氟化和氟可用性相关的材料进行了研究，以了解人类氟摄入量的变化模式。讨论了将来自水和食物的全身及局部氟作用与预防性治疗方案中使用的氟制剂中的氟作用区分开来的困难。建议水氟化是一个经过充分验证的方案，应继续实施，但对个体控制下的氟补充方案应进行仔细评估，如使用，应限于前牙釉质形成分泌期正常结束后的时期，补充剂应在萌出前成熟期开始，并持续到恒牙萌出完成。尽管补充剂也可为牙齿提供局部氟源，这取决于补充剂的服用方式及其在口腔中停留的时间，但也认可其他局部提供氟的方法，并且这些方法应贯穿一生。关于流行病学研究，建议重新审视1971年含氟牙膏出现之前收集的数据。
