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梭形细胞脂肪瘤呈现双相模式——病例报告。

Spindle cell lipoma showing biphasic pattern--a case report.

作者信息

Hattori Koshi, Hatori Masahito, Hosaka Masami, Watanabe Mika, Smith Richard A, Kokubun Shoichi

机构信息

Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan.

出版信息

Ups J Med Sci. 2005;110(2):173-8.

Abstract

This is a case report of a rare spindle cell lipoma (SCL) showing an unusual biphasic pattern with radiological findings and histological features. SCL is most common in men between the ages of 45 and 65 and it is reported that the tumor has a tendency to occur in the posterior neck area. This case was a 75-year old man with a 7 x 5 cm subcutaneous tumor in the posterior neck. Magnetic resonance imaging (MRI) examination demonstrated an unusual biphasic pattern. The signal intensities on T1 and T2 weighted images of the outer layer of the mass were high, and were suppressed on fat suppression views and showed no enhancement after gadolinium (Gd) injection. There was a low signal intensity area of 15 mm in diameter on both T1 and T2 weighted images, in the central part of the mass. This area was well enhanced with the Gd compound. Also macroscopically it could be seen that the excised tumor consisted of two different tissue components. Microscopically, the outer yellowish portion was mainly composed of mature adipose tissue. The inner whitish fibrous portion contained a mixture of small and uniform spindle-shaped cells, collagen fibers, and scattered mature adipose cells. No malignancy was observed. The diagnosis of spindle cell lipoma was made. No recurrence was seen seven months after marginal excision.

摘要

这是一例罕见的梭形细胞脂肪瘤(SCL)病例报告,其具有不寻常的双相模式,伴有影像学表现和组织学特征。SCL在45至65岁男性中最为常见,据报道该肿瘤倾向于发生在后颈部区域。此病例为一名75岁男性,后颈部有一个7×5厘米的皮下肿瘤。磁共振成像(MRI)检查显示出一种不寻常的双相模式。肿块外层在T1加权和T2加权图像上信号强度较高,在脂肪抑制视图上信号被抑制,注射钆(Gd)后无强化。在肿块中央部分,T1加权和T2加权图像上均有一个直径15毫米的低信号强度区域。该区域用Gd化合物强化良好。在大体观察上也可以看出,切除的肿瘤由两种不同的组织成分组成。显微镜下,外层淡黄色部分主要由成熟脂肪组织构成。内层白色纤维部分包含小而均匀的梭形细胞、胶原纤维和散在的成熟脂肪细胞的混合物。未观察到恶性病变。诊断为梭形细胞脂肪瘤。边缘切除七个月后未见复发。

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