甲状旁腺激素检测方法的演变

The evolution of assays for parathyroid hormone.

作者信息

Goodman William G

机构信息

Division of Nephrology, Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California 90095, USA.

出版信息

Semin Dial. 2005 Jul-Aug;18(4):296-301. doi: 10.1111/j.1525-139X.2005.18405.x.

DOI:10.1111/j.1525-139X.2005.18405.x

PMID:16076352

Abstract

Reliable measurements of the concentration of parathyroid hormone (PTH) in serum or plasma are crucial for the effective clinical management of patients with chronic kidney disease (CKD). New PTH assays that increase the specificity of such measurements are now available and are widely utilized. The current review summarizes key technical developments in the evolution of PTH assays. We also discuss the diagnostic value of various methods for measuring PTH in serum or plasma for the assessment of patients with renal bone disease.

摘要

准确测量血清或血浆中甲状旁腺激素（PTH）的浓度对于慢性肾脏病（CKD）患者的有效临床管理至关重要。目前已有能提高此类测量特异性的新型PTH检测方法，且已得到广泛应用。本综述总结了PTH检测方法发展过程中的关键技术进展。我们还讨论了各种测量血清或血浆中PTH的方法在评估肾性骨病患者方面的诊断价值。