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激素疗法对脂溢性皮肤病犬微生物群的影响。

Effects of hormonal therapy on the microbiology of seborrheic dogs.

作者信息

Ihrke P J, Schwartzman R M, Halliwell R E

出版信息

Am J Vet Res. 1979 Oct;40(10):1495-7.

PMID:160764
Abstract

Quantitative and qualitative bacterial assays were performed on the skin of three dogs with endocrine-related primary metabolic seborrhea. After the dogs were treated (thyroid supplementation or castration, bacterial analyses were again performed on the same sites. Before therapy, the dogs had a cutaneous flora composed mainly of Staphylococcus aureus coagulase-positive organisms. After therapy, there was a significantly lower bacterial count, and two of the dogs had floras consisting mainly of coagulase-negative cocci. During the study, the two dogs that reverted bacteriologically to a normal cutaneous microenvironment became normal dermatologically. The third dog improved, but continued to have minor signs of seborrhea.

摘要

对三只患有内分泌相关原发性代谢性皮脂溢的犬的皮肤进行了细菌定量和定性分析。在对这些犬进行治疗(补充甲状腺素或去势)后,再次对相同部位进行细菌分析。治疗前,这些犬的皮肤菌群主要由凝固酶阳性的金黄色葡萄球菌组成。治疗后,细菌数量显著降低,其中两只犬的菌群主要由凝固酶阴性球菌组成。在研究过程中,从细菌学角度恢复到正常皮肤微环境的两只犬在皮肤病学上也恢复了正常。第三只犬有所改善,但仍有轻微的皮脂溢症状。

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