Sasaki A
Department of Obstetrics and Gynecology, Murakami Hospital, Niigata.
Nihon Sanka Fujinka Gakkai Zasshi. 1992 Apr;44(4):427-32.
A clinicopathological and histochemical study has been made on ten cases of adenoma malignum of the cervix. The clinical symptoms and signs of the ten cases were vaginal discharge, vaginal bleeding, and hypertrophy of the cervix. The Papanicolaus classification of the initial smear test obtained by scraping was class III in six cases, class V in two, class IV in one and class II in one. The columnar cells of adenoma malignum showed a weak or negative reaction to high iron diamine (HID) stain and negative to Alcian blue (AB) stain. Normal endocervical columnar cells showed a positive reaction to HID stain and a negative reaction to AB stain. CEA antigen was present in the columnal cells of the adenoma malignum, although normal endocervical glands did not contain CEA.
对10例宫颈恶性腺瘤进行了临床病理和组织化学研究。这10例患者的临床症状和体征为阴道分泌物、阴道出血和宫颈肥大。通过刮片获得的初始涂片检查的帕帕尼科拉乌分类，6例为III级，2例为V级，1例为IV级，1例为II级。恶性腺瘤的柱状细胞对高铁二胺（HID）染色呈弱阳性或阴性反应，对阿尔辛蓝（AB）染色呈阴性反应。正常宫颈管柱状细胞对HID染色呈阳性反应，对AB染色呈阴性反应。恶性腺瘤的柱状细胞中存在癌胚抗原（CEA），而正常宫颈管腺体内不含CEA。
