Weiss David B, Beresford Thomas P, House Robert M
Department of Behavioral Health, Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204, USA.
Curr Treat Options Neurol. 2005 Sep;7(5):419-23. doi: 10.1007/s11940-005-0034-y.
Patient compliance is essential for optimal therapeutic outcome. However, medical noncompliance remains a significant issue in the treatment of many neurologic disorders. Neurologic patients are particularly vulnerable to poor treatment adherence. The chronic and often relapsing and remitting course of neurologic illness creates challenges in maintaining treatment compliance. In addition, comorbid psychiatric conditions can contribute to noncompliance. Decreasing the complexity of dosing schedules, addressing side effect concerns, recognizing financial impact of treatment, and addressing comorbid psychiatric illness all can help to improve compliance. Potentially, the most effective methods to improve compliance include improving the doctor patient relationship, increasing a patient's social support system, and maximizing patient education.
患者依从性对于实现最佳治疗效果至关重要。然而，在许多神经系统疾病的治疗中，医疗不依从仍然是一个重大问题。神经科患者尤其容易出现治疗依从性差的情况。神经系统疾病的慢性病程以及常常复发和缓解的特点给维持治疗依从性带来了挑战。此外，合并的精神疾病状况也可能导致不依从。减少给药方案的复杂性、解决副作用问题、认识到治疗的经济影响以及处理合并的精神疾病，所有这些都有助于提高依从性。潜在地，提高依从性最有效的方法包括改善医患关系、增强患者的社会支持系统以及最大限度地进行患者教育。
