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Clinical implications of the JAK2 V617F mutation in essential thrombocythemia.

作者信息

Antonioli E, Guglielmelli P, Pancrazzi A, Bogani C, Verrucci M, Ponziani V, Longo G, Bosi A, Vannucchi A M

出版信息

Leukemia. 2005 Oct;19(10):1847-9. doi: 10.1038/sj.leu.2403902.

DOI:10.1038/sj.leu.2403902
PMID:16079890
Abstract
摘要

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Clinical implications of the JAK2 V617F mutation in essential thrombocythemia.JAK2 V617F突变在原发性血小板增多症中的临床意义
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The JAK2-V617F mutation and essential thrombocythemia features in a subset of patients with refractory anemia with ring sideroblasts (RARS).伴有环形铁粒幼细胞的难治性贫血(RARS)患者亚组中的JAK2-V617F突变及真性红细胞增多症特征
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JAK2 mutation in essential thrombocythaemia: clinical associations and long-term prognostic relevance.原发性血小板增多症中的JAK2突变:临床关联及长期预后相关性
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JAK2 V617F mutation analysis in different myeloid lineages (granulocytes, platelets, CFU-MK, BFU-E and CFU-GM) in essential thrombocythemia patients.
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JAK2V617F mutation in platelets from essential thrombocythemia patients: correlation with clinical features and analysis of STAT5 phosphorylation status.原发性血小板增多症患者血小板中的JAK2V617F突变:与临床特征的相关性及STAT5磷酸化状态分析
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