Bauer Stephen M, Bauer Richard J, Velazquez Omaida C
University of Pennsylvania, Department of Surgery, Philadelphia, PA 19124, USA.
Vasc Endovascular Surg. 2005 Jul-Aug;39(4):293-306. doi: 10.1177/153857440503900401.
A key central stage of wound healing requires neovascularization of the wound base granulation tissue. In the adult, neovascularization is now known to occur by both angiogenesis and vasculogenesis. Understanding the biology of these 2 processes offers promising new therapeutic options for patients who suffer from chronic, nonhealing ischemic wounds. The authors review the current literature on the processes of angiogenesis and vasculogenesis and how it relates to wound healing.
伤口愈合的一个关键核心阶段需要伤口基底肉芽组织的新血管形成。在成年人中，现在已知新血管形成通过血管生成和血管发生两种方式发生。了解这两个过程的生物学特性为患有慢性、不愈合缺血性伤口的患者提供了有前景的新治疗选择。作者回顾了关于血管生成和血管发生过程以及它们与伤口愈合如何相关的当前文献。
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